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ARNOLD VOSLOO

PORPHYRIA - DRUG LISTS
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SAFE ANESTHETICS

 

The following anesthetics have been researched and verified by anesthesiologists and the list was distributed at a Nurse Anesthetist Conference Spring 1999.

 

The following Anesthetics  are considered safe for general surgery:

 

Anectine [Muscle relaxant]

Curarchloride [Muscle relaxant]

Diprivan [Used for inducing sleep]

Duragesic [A narcotic used for pain control]

Fentanyl [A narcotic used for pain control]

Midazolam [Used for inducing sleep]

Parulon [Muscle relaxant]

Propofol [Used for inducing sleep]

Recuronium [IV neuromuscular blocker]

Sevoflurane [Sleep inhalation gas]

Toredol [Intravenous preparation for pain]

Tubocurarine [Muscle relaxant]

Versed [Used for inducing sleep]

Zemuron [IV neuromuscular blocker]

 

Please note:

Appropriate anesthetic management of porphyria requires knowledge of the type of porphyria (acute vs non-acute), assessment of latent versus active (crisis) phase, awareness of clinical features of porphyric attack, and knowledge of safe pharmacologic intervention. Various types of porphyria require diferent anesthesia and various amounts given. It is not the same for all kinds.

 

 

 B. DRUGS THOUGHT TO BE SAFE FOR USE IN ACUTE PORPHYRIA (1996) 
 

Each bracketed drug ( ) has had conflicting evidence of experimental porphyrinogenicity. Occasionally positive, but mainly negative - none of the drugs in this List have been associated with human porphyric attacks.

 
  A: 
 ACETAZOLAMIDE 

 ACETYLCHOLINE 

 ACTINOMYCIN D 

 ACYCLOVIR 

 ADENOSINE MONOPHOSPHATE 

 ADRENALINE 

 ALCLOFENAC 

 ALLOPURINOL 

 ALPHA TOCOPHERYL ACETATE 

 AMETHOCAINE 

 AMILORIDE 

 AMINOCAPROIC ACID 

 AMINOGLYCOSIDES 

 AMOXYCILLIN 

 AMPHOTERICIN 

 AMPICILLIN 

 ASCORBIC ACID 

 ASPIRIN 

 ATENOLOL 

 ATROPINE 

 AZATHIOPRINE 

  
B: 

 BECLOMETHASONE 

 BENZHEXOL HCl 

 BETA-CAROTENE  

BIGUANIDES 

 (BROMAZEPAM)  

BROMIDES  

BUFLOMEDIL HCl 

 BUMETANIDE  

BUPIVACAINE  

BUPRENORPHINE  

BUSERELIN  

BUTACAINE SO4 

  
C: 

 CANTHAXANTHIN 

 CARBIMAZOLE 

 (CARPIPRAMINE HCl) 

 CHLORAL HYDRATE  

(CHLORMETHIAZOLE)  

(CHLOROQUINE) 

 (CHLOROTHIAZIDE) 

CHLORPHENIRAMINE 

 CHLORPROMAZINE  

CIPROFLOXACIN  

CISAPRIDE 

CISPLATIN 

CLAVULANIC ACID 

 CLOFIBRATE  

CLOMIPHENE  

CLOXACILLIN  

CO-CODAMOL  

CODEINE PHOSPHATE  

COLCHICINE  

(CORTICOSTEROIDS)  

CORTICOTROPHIN (ACTH)  

COUMARINS  

CYCLIZINE  

CYCLOPENTHIAZIDE 

 CYCLOPROPANE  

(CYPROTERONE ACETATE)   
 

D: 

 DANTHRON 

 DESFERRIOXAMINE 

 DEXAMETHASONE 

 (DEXTROMORAMIDE) 

 DEXTROSE 

 DIAMORPHINE 

 DIAZOXIDE 

 DICYCLOMINE HCl 

 DIFLUNISAL 

 DIGOXIN 

 DIHYDROCODEINE 

 DIMERCAPROL 

 DIMETHICONE 

 DINOPROST 

 DIPHENOXYLATE HCl 

 DIPYRIDAMOLE 

 (DISOPYRAMIDE) 

 DOMPERIDONE 

 DOXORUBICIN HCl 

 DROPERIDOL 

  
E: 

 (ESTAZOLAM) 

 ETHACRYNIC ACID  

ETHAMBUTOL  

(ETHINYL OESTRADIOL)  

ETHOHEPTAZINE CITRATE  
 
 ETOPOSIDE 
 
F: 

 FAMOTIDINE 

 FENBRUFEN  
(FENOFIBRATE) 

 FENOPROFEN 

 FENTANYL 

 FLUCYTOSINE 

 FLUMAZENIL  

FLUOXETINE HCl 

 FLURBIPROFEN 

 FLUVOXAMINE MALEATE 

 FOLIC ACID 

 FRUCTOSE 

 FUSIDIC ACID 

 F.S.H.  
  

G: 

 GENTAMICIN  

GLAFENINE 

 GLUCAGON 

 GLUCOSE 

 GLYCERYL TRINITRATE 

 GOSERELIN 

 GUANETHIDINE  

GUANFACINE HCl  
  

H: 

 HAEM ARGINATE 

 (HALOPERIDOL) 

 HEPARIN 

 HEPTAMINOL HCl 

 HEXAMINE 

 (HYDROCORTISONE)  
  

I: 

 IBUPROFEN  

INDOMETHACIN 

 INSULIN  

IRON   
 

J: 

 JOSAMYCIN 

  
K: 

 (KETAMINE) 

 KETOPROFEN 

 KETOTIFEN  
 

L: 

 LABETALOL 

 L.H.R.H. 

 LIQUORICE 

 LITHIUM SALTS  

LOFEPRAMINE 

 LOPERAMIDE  

(LORAZEPAM)   
 

M: 

 MAGNESIUM-SULPHATE 

 (MEBENDAZOLE) 

 MECAMYLAMINE 

 MECLOFENOXATE HCl 

 MECLOZINE 

 MEFLOQUINE HCl 

 (MELPHALAN) 

 MEPTAZINOL 

 MEQUITAZINE 

 METFORMIN 

 METHADONE 

 (METHOTRIMEPRAZINE) 

 METHYLPHENIDATE 

 METHYLURACIL 

 METIPROPRANOLOL 

 METOPIMAZINE 

 METOPROLOL 

 (METRONIDAZOLE) 

 (MIDAZOLAM) 

 MINAPRINE HCl 

 MINAXOLONE 

 MORPHINE  
 

N:  

NADOLOL  

NAFTIDROFURYL OXALATE 

 (NAPROXEN SODIUM)  

NATAMYCIN 

 NEFOPAM HCl 

 NEOSTIGMINE  

NETILMICIN 

 NIFLUMIC ACID 

 NITROUS OXIDE  

NORFLOXACIN 

  
O:  

OFLOXACIN 

 OXOLINIC ACID 
 
 OXYBUPROCAINE  
(OXYPHENBUTAZONE)  

OXYTOCIN   
 

P:  

(PANCURONIUM BROMIDE)  

PARACETAMOL 

PARALDEHYDE 

 PARAPENZOLATE Br 

 PENICILLAMINE  

PENICILLIN  

PENTOLINIUM  

PERICYAZINE 

 PETHIDINE 

 PHENFORMIN  

PHENOPERIDINE  

PHENTOLAMINE MESYLATE 

 PIPOTHIAZINE PALMITATE 

 PIRACETAM 

 PIRBUTEROL  

PIRENZEPINE  

PIZOTIFEN 

 (PRAZOSIN)  

(PREDNISOLONE)  

PRIMAQUINE  

PROBUCOL 

 PROCAINAMIDE HCl  

PROCAINE  

PROCHLORPERAZINE  

PROGUANIL HCl 

 PROMAZINE  

PROPANTHELINE Br  

PROPOFOL  

PROPRANOLOL  

PROPYLTHIOURACIL  

(PROXYMETACAINE)  

PSEUDOEPHEDRINE HCl  

PYRIDOXINE 

 (PYRIMETHAMINE)  
 

Q: 

 QUINIDINE 

 QUININE  
 

R: 

 (RANITIDINE) 

 RESERPINE 

 RESORCINOL  
 

S: 

 SALBUTAMOL 

 SENNA 

 SODIUM BROMIDE 

 SODIUM Ca EDTA 

 SODIUM FUSIDATE 

 SORBITOL 

 STREPTOMYCIN 

 SULBUTIAMINE 

 SULINDAC 

 SULFADOXINE 

 SUXAMETHONIUM 

  
T: 

 TALAMPICILLIN 

 TEMAZEPAM 

 TETRACAINE 

 (TETRACYCLINES) 

 THIOURACILS 

 THYROXINE 

 TIAPROFENIC ACID 

 TICARCILLIN 

 TIENILIC ACID 

 TIMOLOL MALEATE 

 TOLAZOLINE 

 TRANEXAMIC ACID 

 TRIACETYLOLEANDOMYCIN 

 TRIAMTERENE  

TRIAZOLAM 

 (TRICHLORMETHIAZIDE) 

 TRIFLUOPERAZINE 

 TRIMEPRAZINE TARTRATE 

 TRIMETAZIDINE HCl 

 TRIPELENNAMINE 

 TUBOCURARINE 

  
V: 

 VANCOMYCIN 

 (VINCRISTINE)  

VITAMINS 

  
W: 

 WARFARIN SODIUM  

Z: 

 ZIDOVUDINE 

 ZINC PREPARATIONS (TOPICAL) 
 

 

Porphyria Educational Services

Unsafe Drug List

 

 

ABOUT THIS UNSAFE DRUG LISTING:

The pharmaceutical listing contained herein has been devised without reference to language, societal, cultural, dietary, prescribing or dispensing conditions [including those imposed by law], other than those of the United States, which might affect the information provided.

 

This list of pharmaceuticals contains only the listing of drugs known to be UNSAFE or considered potentially to be UNSAFE for porphyrics.

 

Listing of the pharmaceuticals on this site are due to the actions,precautions, side effects, or interactions of the given medication in relation to porphyria patients, or the drug's action in regard to cytochrome P-450 and it's metabolism in the liver.

 

The listing of these pharmaceuticals is not intended as medical advice for individual problems. It is provided only for porphyria patients making an evaluation as to the risks and benefits of taking a particular drug.

 

The potential for various drugs triggering attacks of acute porphyria is based primarily on clinical evidence. Some conclusions are based upon tests with animals with experimental porphyria.

 

The information about drugs contained in this database is general in nature and is intended for use as an educational aid. It also does not cover all possible uses of a said medicine.

 

*Be reminded that a specific drugs may work well for one porphyria patient and not for another usually due to other existing medical conditions of the particular patient.

 

Porphyria patients and their physicians must make their decisions on the use of medications appropriate to their own circumstances and in view of other existing medical conditions.

 

The following unsafe drug list must serve only as a guide since individual patient reactions to specific drug is complex and unpredictable especially with other existing conditions both related and unrelated to the various porphyrias.

 

Because many new drugs have not been tested, such drugs should be avoided. It often takes up to five years to realize the side effects of many new drugs on the market. If it is critical that an untested drug be used, contact with a porphyria specialist should be made before proceeding to use the drug in question.

 

Drugs marked with an asterisk * have been documented as associated with acute attacks of porphyria.

 

 

*    Indicates that there is evidence that the drug has induced porphyria.

 

 

 

*Acabamate (Meprobamate – generic

 [Acetaminophen]  (*in large doses or long-term use)

Alcohol

Alcuronium

*Adalat ( Nifedipine)

*Aldomet

Alkylating agents

Alesse (birth control)

*Alphaxalone

Alprazolam (Benzo)

Alprazolam Intensol

Aluminum Preparations

*Alurate (Barbiturate)

Amaphen (Barbiturate)

Amern (Progestin)

Amidopyrine

Aminoglutethimide

Aminophylline

Amiodarone

*Amitriptyline

Amobarbital (Barbiturate)

[Amphetamines] [See individual drugs as many are unsafe]

*Amylorbaritone (Verified cause)

Amytal (Barbiturate)

Anabolic steroids

Anabolin

Anadrol

Anavar

Ancalixir (Barbiturate)

Androgens

Anolor-300 (barbiturate)

Anoquan (Barbiturate)

Antrocol (Belladonna/Barbiturate)

Anticonvulsants [ *Neurontin is considered safe.]

Anti-epsilepsy Drugs [Some]

Anti-depressants [Some]

Apo-Flurazepam (Benzo)

Apo - Lorazepam (Benzo)

*Apro - Meprobamate (Meprobamate)

*Apo-Metoclop (Metoclopramate)

Apo- Primidon

Apo-Sulfamethoxazole (Sulfonamide)

Apo-Sufatrim (Sulfonamide)

Apo-Sulfatrin - DS (SUlfonamide)

Apo-Sulfisoxizole (Sulfa)

Aprobarital (Barbiturates)

Aralen (Chloroquine)

Arcet (Barbiturate)

Articaine (conflicting data)

Ascomp w/ Codeine No. 3 (Barbiturate)

Atabrine (Quinacrine)

Ativan (Conflicting evidence) (Benzo)

*Auranofin

*Aurothiomalate

Aygestin (Progestin)

Azaline (Sulfa)

Azapropazone

Azulfidine (Sulfa)

Azulfidine En-Tabs (Sulfa)

 

 

 

B-A-C w/ Codeine (Barbiturate)

Baclofen

Bactrim (Sulfonamide)

Bactrim DS (Sulfonamide)

Bancap (Barbiturate)

Barbita (Barbiturate)

*Barbiturates

Barbidonna (Barbiturate)

Barbidonna-2 (Barbiturate)

Barophen (Barbiturate)

*Bemegride  

Belladenal -S (Barbiturate)

*Belladonna

Bellalphen (Barbiturate)

*Bellergal (Barbiturate)

*Benadryl (Sun intolerance)

Bendrofluazide

Benoxaprofen

Benzbromarone

Benzodiazepines

[Benzylthiouracil]AU OH (conflicting evidence)

[Bepridil] (Calcium Channel Blocker) (conflicting evidence)

Beta-Adrenergic Blocking Agents & Thiazide Diuretics (Contain Sulfa)

Birth Control Pills

Brevicon (Birth control)

Bromocriptine

Bronkolixir (Contains barbiturate)

Bucet (Contains Barbiturate)

Busodium (Contains Barbiturate)

*Buspirone (Warning for liver disease)

*Buspar (Buspirone) (Warning for liver disease)

Busulphan

Butabarbital (Barbiturate)

Butabital w/ Codeine (Barbiturate)

Butabital (Barbiturate)

Butace (Barbiturate)

Butalan (Barbiturate

Butalgen (Barbiturate)

Butibel (Barbiturate)

Butisol (Barbiturate)

*Butylscopolamine (Evidence of triggering attacks)

 

 

Cafergot = PB (Berbiturate/ Ergot)

*Calan (Verapamil/ Calcium Channel Blocker) (Evidence of attacks)

Calcium Channel Blockers

Captopril

*Carbamazepine (Evidence of attacks)

(This is a known Inducer of Cyctochrome P-450)

*Carbromal AU OH (Evidence of attacks)

Cardizem (Diltiazem)

*Carisoprodol (Known to induce attacks

*Carmustine

Cefuroxime (Conflicting evidence)  

Celontin (Methosuximide)

Centrax (Benzo)

[Cephalosporins] (Conflicting evidence)

[Cephalerin] (Conflicting evidence)

[Cephradine] (Conflicting evidence)

Chardonna (Barbiturate)

[Chlorambucil] (Conflicting evidence)

*Chloral Hydrate

*Chloramphenicol (Known inducer)

*Chlordiazepoxide (Benzo (Known Inducer) )

*Chlornezanone (Benzo) (Known Inducer

Chloroform

*Chloroquine (Known inducer)

*Chlorpropamide (Known Inducer)

*Chloramphenicol

(This is an Inducer of Cyctochrome P-450)

Chronovera (Verapamil / Calcium Channel Blocker)

Cimetidine

Cinnarizine

Clemastine

Clindex (Benzo)

Clinoxide (Benzo)

[Clobazam] (Conflicting evidence)

[Clomipramine HCI] (Conflicting evidence)

[Clonazepam] (Benzo) (Conflicting evidence)

*Clopr (Metroclorpramide)

*Clorazepate (Known evidence)

Cocaine

[Colistin] (Conflicting evidence)

Contraceptives -

Cordarine (Amadorone)

*Cotrim (Sulfonamide)

Cotrim DS (Sulfonamide)

Co-Trimoxazole (Sulfonamide)

Crinone (Progestin)

Cyclomen (Danazol)

Cyclophosphamide

Cycloserine  

Cyclosporin  

Cytoxin

 

 

Dalmane (Benzo)

Danazol

Danocrine (Danazol)  

Donnazyme (Known to induce)

Dantrdene

Dantrium

*Dapsone

Daunorubicin

Delaxin (Methocarbamol)

Depakene (Valporic Acid) AP

Depakote

Depro - Provera - (Progestin)

Dexfenfluramine

Dextropropoxyphene

Diazepam (Benzo)

Diazepam Instensol (Benzo)

*Dichloralphenazone

*Diclofenac

*Diclofenac

Dienostrol

Diethylproprion  

Dihydralazine

*Dihydroergotamine

*Dilantin (Phenytoin)

Dilcor - XR (Diltiazem / Calcium channel blocker)

Diltiazem (Calcium channel blocker)

*Dimenhydrinate

Diones

*Diphenhydramine

*Diphenylan (Phenytoin)

Disopyramide

Disulfiram

Divalpoex

Dolmar (Barbiturate)

Donnamor (Barbiturate)

Donnapine (Barbiturate)

Donna-Sed (Barbiturate)

Donnatol (Barbiturate)

Donnatal No. 2 (Barbiturate)

Donnatal Extentabs (Barbiturate)

Donphen (Barbiturate)

[Dothiepin HCI] (Conflicting evidence)

Doxycycline

Duralutin - (Progestin)

*Dydogesterone

 

 

 

*Econazole NO3

Elixophyllin (*Contains Amitriptyline)

*Emex (Metroclopramide)

*Enalapril

Endolor (Barbiturate)

Enflurance

* Epitol (Carbamazepine)

Epromate-M (Meprobamate)

Equagesic (Meprobamate)

* Equanil (Meprobamate)

Equanil Wyseals (Meprobamate)

Ercat (Ergot)

Ergometrine (Ergot)

Ergometrine Maleate (Ergot)

Ergonovine (Ergot)

Ergostat (Ergot)

*Ergot Compounds

Ergotamine (Ergot)

Ergotamine Tartrate (Ergot)

*Erythromycin

*Erythrocin (Erythromycin)

*Erythrocot (Erythromycin)

*Erythromid (Erythromycin)

*Ery-Tabs (Erythromycin)

Eryzole (Sulfonamide)

Esgic (Barbiturate)

Esgic-Plus (Barbiturate)

*Estramustine

Estazolam (Benzo)

Estrogen

Estrostep (Birth control)

Ethamysylate

*Ethanol

*Ethchlorvynol

Ethionamide

*Ethosuximide

*Ethotoin (Hydontoin)  

Etidocaine

Etomidate

Etretinate

Eucalyptus

Ezol (Barbiturate)

 

 

Fansidar (Sulfadoxine)

FBM (Felbamate)

Febatol (Felbamate)

Felbamate

*Feldene (Known to cause rash and light sensitivity to cutaneous porphyrics)

Felodipine (Calcium channel blocker)

Femcet (Barbiturate)

Fenfluramine

Fiorinal (Some forms are Barbiturate containing)

*Flexon (Orphenadrine

*Fluoxymesterone (Androgen)

Flurazepam (Benzo)

Folex (Methotrexate)

Fortabs (Contain barbiturates)

*Frusemide  

*Fulvicin P/G (Griseofulvin)

*Fulvicin U/F (Griseofulvin)

*Furosemide

*Furoside (Furosemide)

 

 

G-1 (Barbiturate)

*Gantanol (Sulfonamide)

Gantrisin (Sulfonamide)

Gemonil (Barbiturate)

Genora (Birth Control)

Gesterol 50 (Progestin)

Gesterol LA (Progestin)

Gliclazide (Sulfonylurea)

*Glipizide (Sulfonylurea)

*Glucamide (Sulfonylurea)

*Glucotroi (Sulfonylurea)

*Glutethimide

*Grifulvin V (Griseofulvin)

*Grisactin (Griseofulvin)

*Grisaction Ultra (Griseofulvin)

*Grisovin-FP - (Griseofulvin)

*Gris-Peg (Griseofulvin)

*Griseofulvin

Gusiphed (Some contain barbiturates)

 

 

 

Halazepam (Benzo)

(Halcion) (Triazolam) (Conflicting evidence)

[Haldol] (Haloperidol) (Conflicting evidence)

[Haloperidol

*Halothane

[Halperon] (Haloperidol) (Conflicting evidence)

Heptogesic (Mepromate)

*Hydantoins

*Hydralazine

*Hydra-Zide (Hydralazine)

*Hydrochlorothiazide

Hydrophed (Hydroxine

*Hydroxychloroquine (Chloroquine)

*Hydroxyzine

Hyosophen (Barbiturate)

Hyprogest (Progestin)

Hyproval P.A. (Progestin)

 

 

Idenal w/ Codeine (Barboiturate)

*Imipramine

Iproniazid

Isobutal (Barbiturate)

Isocet (Barbiturate)

Isolin (Barbiturate)

Isollyl w/ Codeine (Barbiturate)

Isollyl Improved (Barbiturate)

Isometheptene Mucate

Isopap (Barbiturate)

[Isoniazid] (Conflicting evidence)

[Isotamine] (Isoniazid) (Conflicting evidence)

 

 

Kava (Unregulated hebral supplement with conflicting evidence) Keflet (Cephlasporin) (Conflicting evidence

Keflex (Cephlasporin) (Conflicting evidence)

Keftab (Cephlasporin) (COnflicting evidence)

Ketazolam (Benzo)

*Ketoconazole

*K-Flex (Orphenadrine)

Kinesed (Barbiturate)

Ketoconazole

Klonopin (Benzo) (Conflicting evidence)

 

 

Lanifolf (Barbiturate)

Lanorinal (Barbiturate)

Lasix (furosemide)

Lectopam (Benzo)

*Levonorgestrol

Levsin (Barbiturate)

Levin-B (Barbiturate)

Levsinex (Barbiturate)

Librax (Benzo)

Libritabs (Benzo)

Librium (Benzo)

Lidoxide (Benzo)

Lignocaine  

Limbitrol (Benzo)

Limbitrol DS (Benzo)

Loprazolam (Benzo)

Lorazepam (Benzo)

Lorazepam Intensol (Benzo)

Loxapac (Loxapine

Loxapine  

Luminal (Barbiturate)

*Lynestrenol

Lysuride Maleate

 

 

*Macrobid (Nitrofurantoin)

*Macrodontin (Nitrofurantoin)

Malatal (Barbiturate)

Maolate (Chlorapenesin)

Maprotiline

*Marax (COnains barbiturate)

Marbaxin (Muscle relaxant)

*Marflex (Orphenadrine)

Marnal (Barbiturate)

*Maxeran (Metroclopramide)

Mebaral (Barbiturate)

Mebaril (Barbiturate)

Mebeverine

*Mecillinam  

Medigesic (Barbiturate)

*Medi-Tran (Mepromate)

Medilium (Benzo)

*Medroxyprogesterone (Progestin)

Megace (Progestin)

Megace Oral Suspension (Progestin)

Megestrol Acetate (Progestin)

Minaval (Estrogen)

*Mephenytoin (Phenytoin)

Mephobarital (Barbiturate)

Mepivacine

Mepro Analgesic (Meprobamate)

*Meprobamate

Meprogese (Meprobamate)

Meprogesic (Meprobamate)

Meprogesic Q (Meprobamate)

*Meprospan (Meprobamate)

Meprospan 200 (Meprobamate)

Meprospan 400 (Meprobamate)

Mercury Compounds

*Mesantoin (Hydantoin)

Mestrabnol

Metaxalone (Muscle relaxant)

Metharbital (Barbiturate)

Methocarbamol (Muscle relaxant)

Methotrexate

Methoxyflurane  

Methsuximide  

*Methyl Sulphonal  

*Methylprylon

*Methysergide

Methsuximide

*Metoclopramide (Known inducer)

Metopirone (Metyrpone)

Metyrapone (Known inducer)

Meval (Benzo)

Mianserin

*Miconazole

Micrainin (Meprobamate)

Midazolam (Benzo)

Mifepristone (Conflicting evidence)

Milltown (Meprobamate)

[Mifepristone] (COnflictig evidence)

Minoxidil

Mogadon (Benzo)

*Mudran (Barbiturate)

Mudrane (Barbiturate)

Muscle Relaxants

Myleran (Busulfan)  

Myldone (Primidone)

Mysoline (PRimidone)

*Nadrolone

*Nalidixic Acid

Naltrexane

*Nandrolone

Natamycin

Necon (Birth control/estrogen)

Nembutal (1) (Barbiturate)

*Neuramate (Meprobamate)

Nicergoline (Conflicting evidence)

*Nifedipine

*Nikethamide

Nitrazepam (Benzo)

*Nitrofurantoin

Noctec (Chloral hydrate)

Nolex (Guaifensin)

*Nolvadex (Tamoxifen)

*Noradex (Orphenadrine)

Norethin (Birth control)

(An Inducer of Cytochrome P-450)

*Norflex (Orphenadrine)

Norgestrel (Progestin)

Norinyl (Birth control)

Norlestin (Birth control)

Nortripyline (Amitriphyline)

*Norplant (Levonorgestrel)

Novo-Veramil (Verapamil)

Nova -Alprazol (Benzo)

Novobiocin

Novoclopate (Benzo)

Novodipam (Benzo)

Novoflupam (Benzo)

Novolorazem (Benzo)

*Novo - Mepro (Meprobamate)

 

*Octamide (Metroclopramide)

Oestrogens (Hormones)

*Oflex (Orphenadrine)

(This is an Inducer of Cyctochrome P-450)

[Omnicef] (Cephalosporin) (Conflicting evidence)

Oral Contraceptives

*Orphenadrine

Oxandrolone

Oxanamide

Oxatomide  

[Oxazepam] (Benzo) (Conflicting evidence)

*Oxtripylline

Oxybutynin

Oxycodone

*Oxymetazoline

*Oxymethalone

*Oxyphenbutazone

Oxytetracycline

 

 

 

Paraflex (Chloroxazone)

Paramethadione

Pargyline

*Pax 400 (Meprobamate)

Paxipam (Benzo)

Pediazole (Sulfonamide)

*Peganone (Hydantoin)

*Pentazocine

Pentobarbital (Barbiturate)

Peptol (Cimetidine)

Perhexiline

*Pergolide (Ergot)

Phenacetin

Phenaphen w/ Codeine 2 (Barbiturate)

Phenaphen w/ Codeine 3 (Barbiturate)

Phenaphen w/ Codeine 4 (Barbiturate)

Phenergan (Promethazine)

Phenobarital (Barbiturate) (Is an Inducer of Cyctochrome P-450)

Phenobaritone (Barbiturate)

*Phenobartbiton (Barbiturate)

Pheno-Bella (Barbiturate)

Phenoxybenzamine

*Phensuxmide

*Phenylbutazone

Phenylhydrazine  

*Phenytoin

Phrenillin (Barbiturate)

Phrenillin Forte (Barbiturate)

*Piperazine (Estrogen)

*Piroxicam  

*Pivmecillinam

Placidyl (Ethchlorvynol)

*Plaquenil (Hydroxychloroquine)

PMS Diazapam (Benzo)

PMS Primadone (Primidone)

PMS Sulfasalazine (Sulfonamide)

PMS Sulfasalazine EC (Sulfonamide)

Prazepam (Benzo)

(Is an Inducer of Cytochrome P-450)

Premarin (Estrogen)

*Premphase (Estrogen)

*Prempro (Estrogen)

Prenylamine

*Prilocine

Prilosec (Omeprazole)

*Primidone

*Probate (Meprobate)

[Probenecid] (Conflicting evidence)

*Procardia (Calcium channel blocker)

Pro-Depo (Progestin)

Prodrox (Progestin)

*Progestaject (Progestin)

*Progesterone

*Progestilin (Progestin)

Progestins/Synthetic

Progabide

*Progestin

Proloprim (Trimethoprim)

Promethazine

[Propanidid] (Conflicting evidence)

ProSom (Benzo)

Protrin (Sulfonamide)

Provera (Progestin)

*Pyrazinamide

*Pyrazolone

Pyrrocaine

 

 

Q-gesic (Meprobamate)

Quazepam (Benzo)

Quinalbarbital (Barbiturate)

Quinalbarbitone (Barbiturate)

Quinacrine (Known to induce attacks)

 

 

Ranitidine

*Reclomide (Metoclopramide)

*Reglan (Metoclopramide)

Rela (Carisoprodol)

[Relafen] (Conflicting evidence)

Relaxadon (Barbiturate)

Renedil (Calcium channel blocker)

Renoquid (Sulfonamide)

Repan (Barbiturate)

Restoril (Benzo)

Rheumatrex (Methotrexate)

*Ridura (Gold Compound)

] Rifampin APF (Is an Inducer of Cytochrome P-450)

Ritalin

Rivotril (Benzo)

Robamol (Muscle relaxant)

Robaxin (Muscle relaxant)

Robaxisal

Robaxaxin (Muscle relaxant)

Robomol (Muscle relaxant)

Roubac (Sulfonamide)

 

 

 

Salazopyrin (Sulfa drug)

Salazosulfapyridine (Sulfa drug)

Salicylazosulfapyridine (Sulfa drug)

Sandimmune (Cyclosporin)

Sarisol No. 2 (Barbiturate)

S.A.S.-500 (Sulfa drug)

S.A.S. Enteric-500 (Sulfa drug) Secobarital (Barbiturate) (Inducer of Cytochrome P-450)

Seconal (Barbiturate)

*Sedabamate (Metprobamate)

Sedapap (Barbiturate)

Sedatives APF

Septocaine[ ] (Cnflicting evidence)

Septra (Sulfa drug)

Septra DS (Sulfa drug)

Serax (Benzo)

Sertan (Primadone)

Sibbelium (Calcium channel blocker)

Simvastatin

SMZ-TMP (Sulfonamide)

Sodol (Carisoprodol)

Sodium Aurothiomalate

Sodium Oxybate

*Sodium Stilogluconate

[Sodium Valproate] (Conflictig evidence)

Solfoton (Barbiturate)

Sollum (Benzo)

Somnol (Benzo)

Sopridol (Carisprodol)

*Soridol (Carisprodol)

Spaslin (Barbiturate)

Spasmolin (Barbiturate)

Spasmorphen (Barbiturate)

Spasquid (Barbiturate)

*Spironolactone

Stanozolol

Succinimides

Sulfacytine (Sulfa drug)

Sulfadiazine (Sulfa drug)

*Sulfadimethoxine (Sulfa drug)

*Sulfadimidine (Sulfa drug)

*Sulfadoxine (Sulfa drug)

*Sulfafurazole (Sulfa drug)

*Sulfamerazine (Sulfa drug)

*Sulfamethizole (Sulfa drug)

Sulfamethoprin (Sulfonamide)

Sulfamethoprin DS (Sulfonamide)

*Sulfamethoxazole (Sulfa drug)

*Sulfamoxole (Sulfa drug)

Sulfaprim (Sulfonamide)

Sulfaprim DS (Sulphonamide)

*Sulfasalazine (Sulfa drug)

*Sulfathiazole (Sulfa drug)

Sulfatrim (Sulfonamide)

*Sulfinpurazone (Slfa drug)

Sulfisoxazole (Sulfa drug)

Sulfonamide-antibiotics

Sulfoxaprim (Sulfa drug)

Sulfoxaprim DS (Sulpha drug)

Sulmeprim (Sulphonamide)

*Sulphacetamide

*Sulphadiazine

*Sulphadimidine  

*Sulphadoxine

*Sulphamethoxazole

*Sulphasalazine

*Sulphonylureas

Sulphinpyrazone Sulphride

Sulthiame

Sultopride

Susano (Barbiturate)

 

 

T-Quill (Benzo)

Tagament (Cimetidine)

Tabutal (Barbiturate)

*Tamoxifen

Tecnal (Barbiturate)

Tedral (C0ntain barbiturate)

Tedral SA (Contains barbiturate)

Tedrigen (Contains barbiturate)

Teev (Androgen)

*Tega-Flex (Orphenadrine)

*Tegretol (Carbamazepine)

TEH Compound (Contains Hydoxyzine)

Temazepam (Benzo) (Conflicting evidence)

Tencet (Barbiturate)

T.E.P. (Barbiturate)

*Terfenadine

Tes Est Cyp (Androgen / Estrogen)

Testa - C (Androgen)

Testamone (Androgen)

Testaqua (Androgen)

Test-Estro Cyplonate (Androgen / Estrogen)

Testex (Androgen)

Testroderm (Androgen)

Testoject - 50 (Androgen)

Testoject LA (Androgen)

Testred (Androgen)

Testred-Cyplonate (Androgen)

Testin - PA (Androgen)

Theodrine (Barbiturate)

Theodrine Pediatric (Barbiturate)

Theofed (Barbiturate)

Theofedral (Barbiturate)

Theomax (Hydroxyzine)

*Theophyllline (Some combinations of this drug contain baribiturates)

Thiosulfil Forte (Sulfonamide)

Tiazac (Calcium channel blocker)

Tilidat

Tinidazole

*Tolazamide (Sulfa drug)

*Tolbutamide

*Tolinase (Sulfa drug)

T-Quil (Benzo)

[Tramadol] (Conflicting evidence)

*Trancot (Meprobamate)

*Tranmep (Meprobamate)

Tranquilizers (Classification)

(Include Hydroxyzine, Loxapine, Meprobamate, Benzos) APF

Tranqulgesic (Meprobamate)

*Tranxene (Benzo)

Tranxene T-Tab (Benzo)

Tranxene - SD (Benzo)

Tranylcypromine

Trazodone

Trazodone

Triad (Barbiturate)

Triapin (Barbiturate)

Triavil (Amitripyline)

Triazole (Sulfonamide)

Triazole DS (Sulfonamide)

Tri-Hydroserpine (Hydoxyzine)

Tri-Levlen (Birth Control)

Trime-thadone (Conflicting evidence)

Trimeth-Sulfa (Sulfonamide)

Trisulfam (Sulfonamide)

Trivora (Birth Control)

Troxidone

Tuinal (Barbiturate)

Two-Dyne (Barbiturate)

Tylosterone (Androgen / Estrogen)

 

 

 

*Ultram (Tramadol)

Urobak (Sulfonamide)

Uroplus DS (Sulfonamide)

Uroplus SS (Sulfonamide)

Urotoin (Nitrofurantoin)

 

 

Valergen 40 (Estrogen)

Valertest No. 1 (Androgen / Estrogen)

Valium (Benzo)

Valproate

*Valproic Acid

Valpromide

Valrelease (Benzo)

Vantin (Cephalsporin)

[Vascor] (Calcium channel blocker) (Conflicting evidence)

[Velosef] (Cephalosporin)

*Verapamil (Calcium channel blocker)

*Verelan (Verapamil) (Calcium channel blocker)

Vibutal (Barbiturate)

Viloxazine

[Vinblastine] (Conflicting evidence)

[Vincristine] (Conflicting evidence)

*Vistaril (Hydroxyzine)

Vivol (Benzo)

 

 

 

Wehgen (Estrogen)

Wigraine (Ergot)

Winstrol (Androgen)

 

 

 

Xanax (Benzo)

 

 

Zapex (Benzo)

Zebrax (Benzo)

Zetran (Benzo)

*Zoloft (Carries warning for liver disease patients)

Zovia (Birth control)

Arnold's Angel